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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOLC1
All Species:
16.67
Human Site:
S291
Identified Species:
28.21
UniProt:
Q14978
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14978
NP_004732.2
699
73603
S291
N
K
P
G
P
Y
S
S
V
P
P
P
S
A
P
Chimpanzee
Pan troglodytes
XP_001171017
700
73581
S292
N
K
P
G
P
Y
S
S
V
P
P
P
S
A
P
Rhesus Macaque
Macaca mulatta
XP_001112196
701
73703
S292
N
K
P
G
P
Y
S
S
V
P
P
P
S
A
P
Dog
Lupus familis
XP_851848
704
74723
S298
K
K
P
G
P
Y
S
S
V
P
P
P
S
V
A
Cat
Felis silvestris
Mouse
Mus musculus
O08784
1320
134983
G739
V
P
A
A
G
K
A
G
A
P
A
T
Q
A
Q
Rat
Rattus norvegicus
P41777
704
73545
S301
K
K
A
G
P
Y
S
S
V
P
P
P
S
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511079
669
69188
Q245
S
S
E
E
E
E
E
Q
Q
Q
R
K
L
A
A
Chicken
Gallus gallus
XP_421630
694
72200
A274
P
K
S
G
Q
Y
S
A
V
P
P
P
Q
A
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689627
1001
102013
S496
D
D
S
S
S
S
D
S
E
S
S
E
D
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730693
686
70584
P249
A
V
Q
P
A
A
K
P
A
P
K
A
A
A
S
Honey Bee
Apis mellifera
XP_001120943
685
75016
K267
A
K
P
Q
L
P
I
K
A
K
S
N
I
K
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796224
791
84162
V359
V
K
A
T
P
K
G
V
K
V
N
V
S
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001168628
517
55362
P124
S
G
T
E
A
G
E
P
E
S
K
A
I
E
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32583
406
40997
K13
I
K
V
D
E
V
P
K
L
S
V
K
E
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.2
81.5
N.A.
24.9
74.1
N.A.
50.7
43.6
N.A.
36.6
N.A.
27.3
22
N.A.
34.5
Protein Similarity:
100
98.8
95.5
85.6
N.A.
36.7
81.2
N.A.
60.3
57.5
N.A.
47.5
N.A.
42.3
42.9
N.A.
47.9
P-Site Identity:
100
100
100
80
N.A.
13.3
73.3
N.A.
6.6
60
N.A.
6.6
N.A.
13.3
13.3
N.A.
20
P-Site Similarity:
100
100
100
80
N.A.
20
73.3
N.A.
13.3
66.6
N.A.
13.3
N.A.
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
23.6
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
40.9
N.A.
N.A.
39.4
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
22
8
15
8
8
8
22
0
8
15
8
50
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
0
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
8
15
15
8
15
0
15
0
0
8
8
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
43
8
8
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
0
15
0
0
% I
% Lys:
15
65
0
0
0
15
8
15
8
8
15
15
0
22
0
% K
% Leu:
0
0
0
0
8
0
0
0
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
22
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
8
8
36
8
43
8
8
15
0
58
43
43
0
0
29
% P
% Gln:
0
0
8
8
8
0
0
8
8
8
0
0
15
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
15
8
15
8
8
8
43
43
0
22
15
0
43
0
22
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
15
8
8
0
0
8
0
8
43
8
8
8
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
43
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _